63. Fishel R, Ewel A, Lescoe MC. Purified human MSH2 protein binds to DNA containing mismatched nucleotides. Cancer Res 1994; 54: 5539-42.

64. Loeb LA. Microsatellite instability: marker of a mutator phenotype in cancer. Cancer Res 1994; 54: 5059-63.

65. Chu G. Cellular responces to Cisplatin. J Biol Chem 1994; 269: 787-90.

66. Sorenson CM, Eastman A. Influence of cis-Diamminedichloroplatinum (II) on DNA synthesis and cell cycle progression in excision repair proficient and deficient hamster ovary cells. Cancer Res 1988; 48: 6703-7.

67. Li Q, Gardner K, Zhang L, Tsang B, Bostick-Bruton F, Reed E. Cisplatin induction of ERCC-1 mRNA expression in A2780/CP70 human ovarian cancer cells. J Biol Chem 1998, 273 (36): 23419-25.

68. Husain A, He G, Venkatraman ES, Spriggs DR. BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum (II). Cancer Res 1998, 58 (6): 1120-3.

69. Mestdach N, Pommery N, Saucier JM, Hecquet B, Founier C, Slomianny C, Teissier E, Henichart JP. Chemoresistance to doxorubicin and cisplatin in a murine cell line. Analysis of P-Glycoprotein, topoisomerase II activity, glutathione and related enzymes. Anticancer Res 1994; 14: 869-74.

70. Kondo H, Kanzawa F, Nishio K, Saito S, Saijo N. In vitro and in vivo effects of cisplatin and etoposide in combination on small cell lung cancer cell lines. Jpn J Cancer Res 1994; 85: 1050-6.

71. Jong S, Timmer-Bosscha H, Vries EGE, Mulder NH. Effect of novobiocin on cisplatin cytotoxicity and DNA interstrand cross-link formation in a cisplatin-resistant, small-cell lung carcinoma cell line. Int J Cancer 1993; 53: 110-7.

72. Guchelaar H-J, Timmer-Bosscha H, Dam-Meiring A, Uges DRA, Oosterhuis JW, Vries EGE Mulder NH. Enhancement of cisplatin and etoposide cytotoxicity after all-trans retinoic-acid-induced cellular differentiation of a murine embryonal carcinoma cell line. Int J Cancer 1993; 55: 442-7.

73. Seki S, Hongo A, Zhang B, Akiyama K, Sarker AH, Kudo T. Inhibition of cisplatin-mediated DNA damage in vitro by ribonucleotides. Jpn J Cancer Res 1993; 84: 462-7.

74. Parekh HK, Simpkins H. The differential expression of citokeratin 18 in cisplatin-sensitive and -resistant human ovarian adenocarcinoma cells and its association with drug sensitivity. Cancer Res 1995; 55: 5203-6.

75. Mirakhur B, Parekh HK, Simpkins H. Expression of the cisplatin resistance phenotype in a human ovarian carcinoma cell line segregates with chromosomes 11 and 16. Cancer Res 1996; 56: 2256-62.

76. Mueller H, Eppeberger U. The dual role of mutant p 53 protein in chemosensitivity of human cancers. Anticancer Res 1996, 16 (6B): 3845-8.

77. Kawasaki t, Tomita Y, Bilim V, Takeda M, Takahashi K, Kumanishi T. Abrogation of apoptosis induced by DNA-damaging agents in human bladder-cancer cell lines with p 21/WAF1/CIP1 and/or p 53 gene alterations. Int J Cancer 1996, 68 (4): 501-5.

78. Kondo S, Barna BP, Kondo Y, Tanaka Y, Casey G, Liu J, Morimura T, Kaakaji R, Peterson JW, Werbel B, Barnett GH. WAF1/CIP1 increases the susceptibility of p 53 non-functional malignant glioma cells to cisplatin-induced apoptosis. Oncogene 1996, 13 (6): 1279-85.

79. Li G, Tang L, Zhou X, Tron V, Ho V. Chemotherapy-induced apoptosis in melanoma cells is p 53 dependent. Melanoma Res 1998, 8 (1): 17-23.

80. Biagosklonny MV, El-Deiry WS. Acute overexpression of wt p 53 facilitates anticancer drug-induced death of cancer and normal cells. Int J Cancer 1998, 75 (6): 933-940.

81. Li R, Sutphin PD, Schwartz D, Matas D, Almog N, Wolkowicz R, Goldginger N, Pei H, Prokocimer M, Rotter V. Mutant p 53 protein interferes with p 53-independent apoptotic pathways. Oncogene 1998, 16 (25): 3269-77.

82. Vasey PA, Jones NA, Jenkins S, Dive C, Broun R. Cisplatin, camptothecin, and taxol sensitivities of cells with p 53-associated multidrug resistance. Mol Pharmacol 1996, 50 (6): 1536-40.

83. Vikhanskaya F, Clerico L, Valenti M, Stazione NS, Broggini M, Parodi S, Russo P. Mechanism of resistance to cisplatin in a human ovarian-carcinoma cell line selected for resistance to doxorubicin: possible role of p 53. Int J Cancer 1997, 72 (1): 155-9.

84. Vaisman A, Varchenko M, Said I, Chaney SG. Cell cycle changes associated with formation of Pt-DNA adducts in human ovarian carcinoma cells with different cisplatin sensitivity. Cytometry 1997, 27 (1): 54-64.

85. Siddik ZH, Mims B, Lozano G, Thai G. Independent pathways of p 53 induction by cisplatin and X-rays in a cisplatin-resistant ovarian tumor cell line. Cancer Res 1998, 58 (4): 698-703.

86. Ju JF, Banerjee D, Lenz HJ, Danenberg KD, Schmittgen TC, Spreas CP, Schonthal AH, Manno DJ, Hochhauser D, Bertino JR, Danenberg PV. Restoration of wild-type p 53 activity in p 53-null HL-60 cells confers multidrug sensitivity. Clin Cancer Res 1998, 4 (5): 1315-22.

87. Fajac A, Da Silva J, Ahomadegbe JC, Rateau JG, Bernaudin JF, Riou G, Benard J. Cisplatin-induced apoptosis and p 53 gene status in a cisplatin-resistant human ovarian carcinoma cell line. Int J Cancer 1996, 86 (1): 67-74.

88. Kondo S, Barna BP, Morimura T, Takeuchi J, Yuan J, Akbasak A, Barnett GH. Interleukin-1-beta-converting enzyme mediates cisplatin-induced apoptosis in malignant glioma cells. Cancer Res